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Serum vitamin B12 concentrations were categorized into tertiles rather than using clinical cutoffs for deficiency or elevated levels

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doi: 10.1038/cr.2011.22

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Over 95 serial transfers spanning 16 months, the adapted strain A 2 78 showed a 45% increase in -carotene yield (54 1.95 mg/L) compared to the wild type (21.6 2.11 mg/L), without a major compromise in biomass accumulation