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0.5 g (0.35 mmol) of a pentadecapeptide with the sequence Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala Gly Leu Val (BPC157) was dissolved in 10 ml water containing 29,6 mg of sodium hydrogencarbonate (0.35 mmol), sterile filtered through a 0.2 filter and dried by freeze-drying to give 0.48 g of an off-white solid

Therefore, TMAO can aggravate atherosclerosis formation by affecting the metabolism of bile acid and cholesterol

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(2) batch-specific HPLC chromatogram with resolved peaks for all components

Riphagen S, Gomez X, Gonzales-Martinez C, et al