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By regulating the unpolymerized actin pool, TB-500 acts as a rheostat for cytoskeletal remodeling : on migration or repair signals, sequestered G-actin is released and polymerized at the leading edge of moving cells

Studies treating mild to moderate B12 deficiency in older people have failed to provide cognitive benefits: A clinical trial from the Netherlands measured the cognitive response to B12 supplements in people 70 years old with mild B12 deficiency and MMA levels 320 nmol/l (average: ~450 nmol/l)

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Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinsons and Lewy body diseases

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