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Low IGFBP-2 also acts as a good marker for MetS along with high fasting glucose [254]
It took a while to figure out what was going on, but when they reduced her B12 dose to 250mcg three times a week and had her take it in the late morning (when kidneys work best), her symptoms improved and her kidney function stabilized
If you have a Vitamin B12 deficiency and also suffer from GI related symptoms then it is advisable to have a practitioner order some functional lab tests to identify potential gut infections or other imbalances
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