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These studies suggested that this novel SFK-dependent pathway involves the activation of PLC, and a subsequent release of inositol 1,4,5-triphosphate (IP 3 ) and diacylglycerol which leads to an increase in the cytoplasmic calcium ion concentration-activating Ras guanine nucleotide exchange factor RasGRP1

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NAD+ is a coenzyme essential for various biological processes, including DNA repair, mitochondrial function, and reducing oxidative stress