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Cohen D, Goldberg M, Gulati A, and Ferri FF

However, at higher concentrations (10 mg/dl), uric acid promotes cellular senescence and downregulates EGF/EGFR signaling

Some pilot studies suggest preservation of brain metabolism, while others have not demonstrated meaningful cognitive improvement

Tirzepatide (15 mg weekly) drives 15.7% weight loss over 72 weeks in patients with obesity and T2D (45) and 22.5% weight loss in patients with obesity alone (46)

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