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It may be because substance-use disorders are built upon abnormal glutamate neurotransmission, and that schizophrenia heavily features dopaminergic dysfunction ( 22 )

It is not a hormone, not a peptide hormone analog, and not approved for any human therapeutic use by any regulatory authority as of 2025

doi:10.1126/science.8351519

Y.LandrethG

However, elevated levels may indicate underlying conditions such as liver disease, haematological disorders, or kidney impairment that require medical investigation and management