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Recently, less traditional transcriptional roles for AR, such as those impacting non-coding RNAs as well as transcription-independent roles that include AR-dependent splicing programs and translation control have been recognized to contribute to aggressive CaP features and treatment resistance

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When clinically studied at a 0.1% topical GHK-Cu concentration, it increased collagen production by 51%, skin firmness by 25%, and skin density by 23% in 84 days