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10.1111/nep.13114 15 RoffeyS

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Research interest areas that appear in the scientific literature include: Muscle protein synthesis and body composition changes in adults with GH deficiency Recovery from musculoskeletal injury given GHs role in tissue repair Sleep quality, given GHs relationship to slow-wave sleep architecture Metabolic function, particularly lean mass preservation in aging populations Important caveat: most human studies are small, short-term, and conducted in specific populations (often GH-deficient patients)

Using the GLP-QR agonist Exendin-4 (Exn-4) increased firing rates in arcuate nucleus (ARC) GLP-1R and POMC neurons, and the chemogenetic activation of ARC GLP-1R neurons significantly reduced food intake [132]