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J Biol Chem 272(49):3061530618 Gan L, Yang XL, Liu Q, Xu HB (2005) Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells

Studies have found that this difference in susceptibility is caused by higher expression of the INS gene and proinsulin protein in the thymus and lower expression in the pancreas of human patients harboring the class III allele compared to class I expression

At the same time, research on amino acid metabolism in macrophages has still been focused primarily on amino acids such as Arg and Trp, while studies on other amino acids remain relatively limited, and their specific mechanisms still require further elucidation

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A major limitation of many of the studies investigating adjuvant treatment for HS is indirect assessment of the efficacy of the molecule under investigation