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There are four clinically relevant molecular subtypes of invasive ductal carcinoma: luminal A, luminal B, HER2/neu, and basal-like breast cancer, based on the expression of the hormone receptors: estrogen (ER) and progesterone (PR), as well as the human epidermal growth factor (HER2)

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and the MAPK/ERK pathway, involved in cell proliferation and differentiation