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Finally, a recent review by Dayan (2025) demonstrates the need to balance the psychological and ethical considerations in aesthetic medicine, distinguishing between objective beauty and subjective attractiveness while emphasizing the importance of a patients self-confidence in ethical practice [86]

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In addition, Irg1-deficient phagocytes, which cannot produce itaconate, have shown increased susceptibility to M.tb infection, with infected mice exhibiting higher bacterial loads, reduced survival, exacerbated inflammation, extensive necrotizing granuloma formation and elevated neutrophil infiltration in the lungs [104, 105]

Santoro A, Calvo JS, Peris-Daz MD, Krel A, Meloni G, Faller P