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However, no differences were observed in isometric torque production, specific torque, or histological measures of myofiber cross-sectional area or collagen deposition across any treatment group
Distinct tissue distribution in pigs of tenascin-X and tenascin-C transcripts
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Future studies should prioritize defining the precise abundance threshold of Akkermansia muciniphila that balances its beneficial and deleterious effects on the intestinal barrier, investigating the molecular mediators (e.g., specific metabolites or surface proteins) that underpin its dual regulatory role, and developing targeted interventions (e.g., precision probiotics or microbiota modulators) to sustain its homeostatic levelswith the goal of ultimately mitigating OA progression via the gut-joint axis
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