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There were subtle differences in the most prevalent and relatively abundant genera (i.e., core genera) of the bacterial communities from participants who received GR + Myr prior to fecal sampling versus those who received GR alone

APP carriers presented an accumulation of naive T cells at the expense of the contraction of highly differentiated memory cells, accompanied by a remodeling of the plasma metabolome that favored a decrease in the NAD + precursor trigonelline 27 , shown to restore memory function in 5xFAD mice 67 , along with an increase in adenosine, reported to mediate non-canonical CD38-dependent immunosuppression 68

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