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Veterinary Dermatology

However, the combination treatment increased liver X receptor alpha (LXR), a nuclear receptor essential for bile acid synthesis, cholesterol efflux, and lipid metabolism regulation

In most ferroptosis-related conditions including hepatic steatosis, cardiomyopathy, spinal cord injury, and BPA-induced liver damage, both enzymes are simultaneously upregulated, promoting lipid peroxidation and enhancing ferroptotic signaling (7073)

Anti-inflammatory effect of the Si-based agent might be related to the hydrogen produced from the Si-based agent

351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE