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Meanwhile, in January 1996 the first rodent study suggested that GLP-1 could be a central regulator of feeding behavior and satiety based on intracerebroventricular injection studies [4], but soon thereafter the results of other rodent studies using peripherally injected GLP-1 argued against an appetite effect [5]

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Foundayo showed about 12% body weight reduction in trials, and oral Wegovy came in around 14%

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Yin W.L., Bain S.C., Min T

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