In addition to modulation of energy metabolism and mitochondrial function in CRC, we demonstrate for the first time, that metformin significantly radiosensitises both radiosensitive HCT116 colon cancer and radioresistant SW837 rectal cancer cells to a clinically-relevant dose of 1.8 Gy X-ray radiation
Our pre-clinical findings provide rationale for the advancement of pharmacotherapeutic antioxidant treatments aimed at circumventing or perhaps reversing the deleterious effects of adolescent THC exposure
Our team specializes in liquid rhinoplasty, comprehensive face balancing, mini liquid facelifts, and lip rejuvenation & augmentation
Ongoing surveillance is only recommended if extensive gastric atrophy, intestinal metaplasia, or additional risk factors are identified
Freezing and thawing can change protein stability and promote aggregation, and the effect depends on the formulation. What signs mean a reconstituted vial should be discarded