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121(4): 53946 Rebouche CJ, Lombard KA, Chenard CA

113 Intestinal flora disorders may compromise the BBB integrity due to the decreased expression of tight junction proteins

noted that plasma levels of -MSH (a melanocortin agonist, like -endorphin, also encoded within POMC) varied across different-pigmented mice, paralleling -endorphin levels (i.e., higher -MSH levels in mice with more melanocytes

Reduces Pigmentation & Dark Spots It helps lighten: Sunspots Acne marks Tan Uneven patches Melasma (in some cases) 3

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