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Mechanisms include: UVB: Direct DNA damage (CPDs) that impair fibroblast function UVA: Oxidative stress that degrades collagen and elastin Anatomical reflection: Light bounces into the orbital area, increasing cumulative exposure This is why we stress sunscreen around the eye area is not optional

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Replenishing glutathione levels through oral liposomal and IV administration accelerates recovery, particularly in patients with genetic variations that impair glutathione production

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GHK-Cu (Glycine-Histidine-Lysine-Copper) A naturally occurring copper-binding tripeptide found in human plasma that declines with age