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BMC Psychiatry 22 , 248 (2022)

Witte ME, Nijland PG, Drexhage JAR, Gerritsen W, Geerts D, van het Hof B, Reijerkerk A, de Vries HE, van der Valk P, van Horssen J (2013) Reduced expression of PGC-1partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

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This study evaluated the therapeutic potential of non-gene-edited human chemically induced pluripotent stem cell-derived neural stem cells (hCiPSC-NSCs) in a prenatal valproic acid (VPA)-induced rat model of ASD, using a dual-pathway administration strategy (intravenous systemic delivery combined with an intracerebroventricular boost)