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2017;7:e1080

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15 HeirmanI.GinnebergeD.Brigelius-FlohR.HendrickxN.AgostinisP.BrouckaertP.et al (2006)

The clinical application requires understanding both the peptide's mechanisms and appropriate dosing strategies for specific conditions

Because GCLC floxed X Iba1-Cre mice died early (around 34 months of age) due to developmental defects, we could not assess the effect of microglial GCLC-deficiency on brain atrophy