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Evidence from a randomized, double-blind, placebo-controlled, cross-over study in 24 resistance-trained males found that a single 4.5 g dose of GPLC significantly improved peak and mean power output during repeated Wingate sprints

Specifically, in skeletal muscle, age-associated reductions in NRF2 target gene expression is accompanied by increased hydrogen peroxide and 4-hydroxynonenal (4-HNE) production, glutathione depletion, and oxidant damage (Safdar et al., 2010)

Current Opinions in Pediatrics

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Connective Tissue and Vascular Biology Healthy connective tissues depend upon coordinated communication between structural cells, extracellular matrix components, and vascular networks