KLOW may be purchased in the UK when supplied and used strictly for laboratory research purposes
To quantify total PDHc-E2 and OGDHc-E2, lipoate blots were stripped using Restore Western Blot Stripping Buffer (Thermo Fisher Scientific, 21059), reblocked in 5% skim milk in PBST and re-immunoblotted using appropriate primary antibodies
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Given that both GIP receptor agonism and antagonism have only been thoroughly investigated in combination with GLP-1 receptor agonism, long-term clinical studies of GIP receptor antagonism alone are needed to evaluate the adverse effect profile
