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Previously, investigators have shown that upon glucose challenge, DP-IV -/- mice have improved glucose tolerance, increased insulin, and increased active GLP-1, consistent with the role of DP-IV in the regulation of GLP-1

Reducing the intake of sulfur-rich foods, staying hydrated, and consuming probiotics can potentially alleviate the symptom

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Fermentable, viscous fibers aid satiety and can raise endogenous GLP-1 via short-chain fatty acids, but their standalone weight effect is small and GI tolerability is the main formulation limit