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For example, if you wake up in the night with painful cramps, it can affect your sleep

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The coordinated nature of these pathway disruptions is particularly significant, as CSCs often demonstrate remarkable plasticity and can maintain their stem-like properties through compensatory activation of alternative signaling routes when individual pathways are targeted in isolation

Afr J Microbiol Res 5(20):31503156 Huang H-C, Chang T-M (2012) Antioxidative properties and inhibitory effect of Bifidobacterium adolescentis on melanogenesis