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OWL833, an orally active nonpeptide GLP-1 receptor agonist, improves glucose tolerance by increasing insulin secretion and reduces food intake of cynomolgus monkeys

We then performed two-sample MR (2SMR) and Bayesian colocalization analyses to further estimate the causal effect of GLP-1Rs dual- and tri-peptidic agonists on MASLD, its metabolic risk factors, and multiple-organ complications