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Front Pharmacol 2021;12:667753

12 DISCUSSION To date, there are few studies demonstrating utility of topical glutathione in treating hyperpigmentation, oxidative damage, TEWL, and improving skin elasticity

Vegan diets, excessive alcohol use, certain medications, aging, and certain stomach diseases all raise the risk of vitamin B12 insufficiency

We also thoroughly investigated the currently available data on the use of supplements for these concerns and applied that knowledge to inform our picks