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Key Takeaways Dry mouth, bad breath, and taste changes can happen with semaglutide or tirzepatide, though there's no solid clinical proof that the medication directly causes them

Practice Pearl(s) The dosing regimen of glucagon-like peptide-1 (GLP-1) agonists is characterized by careful initiation and titration to ensure optimal glycemic control while minimizing potential adverse effects

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However, we did observe higher increases in serum calcitonin levels, a tumor marker for medullary thyroid carcinoma, with increased doses of tirzepatide compared to placebo