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Kitamura et al., 2003

Sustained elevation in heart rate, even by 5-10 beats per minute, increases long-term cardiovascular risk

Closely monitor potassium levels in patients at risk of hypokalemia and treat if indicated

Other potential contributing factors include dehydration (especially if gastrointestinal symptoms are present) and the body's adaptation period to the medication

These treatments are designed to target the underlying factors that make weight loss challenging, offering both metabolic support and appetite regulation