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doi: 10.1016/j.cmet.2012.12.011 10 BernsteinA

A comparative study suggested that patients with T2DM treated with SGLT2 inhibitors may have an even lower risk of developing DED than those on GLP-1RAs [127]

The relative ranking of dose combinations remained consistent, with the highest probabilities observed for semaglutide 2.4 mg vs tirzepatide 10 mg and semaglutide 7.2 mg vs tirzepatide 15 mg

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Individuals with a history of seizure disorders, alcohol or opioid dependence, or certain psychiatric conditions should avoid naltrexone or require specialized oversight