More than 200 symptoms across multiple organ systems have been associated with LC, with the most commonly reported clinical symptoms being post-exertional malaise, fatigue, difficulty concentrating, memory changes, headaches, palpitations, chest pain, dizziness when standing up (lightheadedness), sleep disturbances, difficulty breathing or shortness of breath (dyspnea), cough, problems with taste and smell, bloating, constipation, diarrhea, stomach pain, fever, muscle and joint pains, pins-and-needles feelings, rash, and changes in menstrual cycles (Table 1) (4, 15, 16)
Glutathione is a key player in Phase II of this process
Any disturbance in the coordination pathway can inhibit normal growth and increase the risk of developing other medical conditions
Oral administration of Codonopsis pilosula balanced cytokine expression by inhibiting IL-17A, IL-17F, IL-6, IL-22, and TNF-a, while increasing TGF-b and IL-10