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These include: Nausea (often most pronounced during dose escalation) Vomiting and diarrhoea Constipation Abdominal discomfort and bloating Reduced appetite (therapeutic effect but may be excessive) These symptoms typically diminish over 48 weeks as tolerance develops

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GLP-1 medications reduce arthritis pain primarily through weight loss, which decreases mechanical stress on joints and reduces inflammatory molecules produced by fat tissue

The intestine, which produces incretin hormones, is the central regulator of glucose metabolism

These strategies can make a big difference, but its not always easy to know which ones are right for your IBS type