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Another mechanism through which Aos contribute to oxidative stress involves the activation of toll-like receptor 4 (TLR4) on microglia [87], the brains resident innate immune cells

They observed mobilization of Pax7+ satellite cells, improved fibrillar regeneration, and a reduction in fibrosis

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Explanation: Skin tone is primarily determined by genetics, and there is no natural or permanent way to drastically alter it