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Genomic instability Before discussing cellular mechanism, we briefly introduce an important notion of genomic alteration in senescence

Animal Studies: Strong Results in Obese Rodent Models The foundational animal work was conducted in obese Zucker rats and ob/ob mice, two standard models for studying obesity

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Based on the experience of the observer, the specific morphological features of the cytoplasmic vacuolation may be sufficiently consistent with intracytoplasmic lipid accumulation to warrant a presumptive diagnosis of fatty change

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