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Consequently, senolytics, drugs that selectively kill senescent cells, have broad therapeutic appeal

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Front Plant Sci 9:1178 Jantan I, Haque MA, Arshad L et al (2021) Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways

The biological roles proposed for GHK-Cu in the research literature have included effects on collagen and extracellular matrix synthesis (through copper-dependent enzymes including lysyl oxidase), on antioxidant gene networks (where copper participates in both prooxidant and antioxidant chemistry depending on context), on growth factor activity in tissue repair, on hair follicle biology, and on broader transcriptional programs characterized in microarray and RNA-seq studies

Another review comparing the two drugs shows 11% loss of body weight for tirzepatide and 7% with semaglutide over 36 weeks