Activated M1 (or pro-inflammatory) microglia are part of an inflammatory cascade that includes upregulation of pro-inflammatory genes, release of pro-inflammatory cytokines, and generation of ROS, which may, under prolonged conditions, contribute to the neuroinflammation observed in AD brain [97]
The same pattern is expected for tirzepatide
Pro Tip: Always track your energy and focus patterns over weeks, not just days
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Fat supports hormone function, helps your body absorb nutrients, and can help you feel satisfied longer