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Histologic evidence from liver biopsiesthe definitive method for diagnosing and staging NASHhas been more limited but encouraging

Compromised intestinal epithelial barrier due to intestinal epithelial-specific loss of JAM-A induces adaptive immune compensation that protects from colitis The findings in mice manipulated for MLCK or occludin expression differed from those obtained in mice lacking the JAM-A (encoded by F11r)

When those pieces align, the research makes a strong case for it

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