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Their receptors are just more sensitive, said coauthor Adriana Hung, M.D., M.P.H., a nephrologist and epidemiologist at Vanderbilt

Efficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial

By the 1980s, the specific role of GLP-1 in glucose metabolism was understood, paving the way for the development of GLP-1 receptor agonists