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These findings support the relevance of MGBA mechanisms in BD pathophysiology, implicating both immune and metabolic pathways as shown in Table 8, and are conceptually illustrated through the microbiotaimmunemetabolicbrain axis model (Figure 6

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The fundamental issue is the lack of education, awareness and respect demonstrated by many GPs to patients seeking a diagnosis or treatment

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Access this article Similar content being viewed by others References Teede HJ, Misso ML, Costello MF, et al