If GI side effects appear, depending upon the severity of GI events, either dose can be reduced or maintained or treatment can be stopped for some time and started again after a few days
For a 150-pound person, this translates to 15 pounds, achievable in 1220 weeks at therapeutic dose when combined with lifestyle modification
Regular follow-up appointments allow assessment of weight loss progress, medication tolerability, and cardiovascular risk factor control
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Skipping doses, varying injection times significantly, or taking days off mid-cycle undermines the physiological processes you are trying to support