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Nat Rev Neurol 10(2):115119 Musiek ES, Holtzman DM (2016) Mechanisms linking circadian clocks, sleep, and neurodegeneration

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Shared and dose-dependent histological and morphological changes included desquamation of enterocytes, marked mucus accumulation, hyperaemia in the lamina propria, and substantial villus shortening with mucosal thinning

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