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The FDA approved liraglutide (Victoza) at doses of 0.6 mg, 1.2 mg, and 1.8 mg daily for T2DM patients with unsatisfactory diet or exercise control, and 2.4 mg and 3 mg as a chronic weight management drug
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In addition, IGF-IR is overexpressed in about 30% of human prostate cancer
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The glucagon-arm effects (active hepatic fat oxidation, raised resting metabolic rate, cardiac BMR contribution) fade in roughly the same window
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