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[16] [17] Potential risks include an increased risk of haemorrhagic stroke and prostate cancer (in men) with long-term use

Research indicates that apigenin effectively inhibits CD38 in mice, leading to significant increases in NAD + levels 143,144

[150] reported that transferrin-conjugated CDs co-loaded with temozolomide and epirubicin produced markedly enhanced cytotoxicity across multiple GBM cell lines compared to single-drug formulations, illustrating the advantage of combined targeting and multi-drug delivery strategies [150]

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