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Drug-makers are specifically seeking to add more pill-based versions of Ozempic, which would appeal to people who do not want injections

The researchers found that low-dose semaglutide (0.25 mg/week for four weeks, 0.5 mg/week for four weeks, and 1 mg for one week) reduced the amount of alcohol consumed during a posttreatment laboratory self-administration task, with medium to large effect sizes for alcohol consumed (grams) and peak breath alcohol concentration (, 0.48 and 0.46, respectively)

Kolnes et al

doi: 10.1177/1060028020935105 127 LinSDengYHuangJLiMSoorannaSRQinMet al

Abbreviations AE: Adverse event AgRP: Agouti-related peptide ALAT: Alanine aminotransferase Anti-CGRP mAbs: Monoclonal antibodies against calcitonin gene-related peptide AP: Area postrema BMI: Body mass index CART: Cocaine- and amphetamine-regulated transcript CGRP: Calcitonin gene-related peptide CSF: Cerebrospinal fluid ENS: Enteric nervous system FUP: Follow-up GCL: Ganglion cell layer GLP-1: Glucagon-like peptide-1 GLP-1-RA: Glucagon-like peptide-1 receptor agonist Hyp: Hypothalamus ICP: Intracranial pressure IIH: Idiopathic intracranial hypertension IIH-WOP: Idiopathic intracranial hypertension without papilledema MHD: Monthly headache days NPY: Neuropeptide Y NTS: Nucleus tractus solitarii OCT: Optical coherence tomography ONSD: Optic nerve sheath diameter POMS: Proopiomelanocortin pRNFL: Peripapillary retinal nerve fiber layer pwIIH: Patients with idiopathic intracranial hypertension SFO: Subfornical organ UCWM: Usual care weight management ULN: Upper limit of normal VIIH: Vienna Idiopathic Intracranial Hypertension References Mollan SP et al (2018) Idiopathic intracranial hypertension: consensus guidelines on management