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10.1155/2016/2920108 [DOI] [PMC free article] [PubMed] [Google Scholar] 57.Opalka JR, Gellerich FN, Zierz S

Since 85% of transmethylation reactions and up to 48% of methionine metabolism occurs in the liver, hepatic SAMe availability is essential

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They are implicated in the regulation of several functions, including nociception, diuresis, mood, feeding, and neuroendocrine secretions (Tejeda et al., 2012

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