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While existing systematic reviews and retrospective cohorts have not identified stable, potent teratogenic signals, the heterogeneity in exposure windows, drug types/dosages, and baseline metabolic riskscompounded by residual confoundingrenders any safe vs

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Another Harvard-led study found a 29% increase in coronary heart disease risk for each 0.5-point increase in HbA1c above 5.0%. Those numbers matter even when results technically fall within the normal range

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How a Doctor May Manage GLP-1 Side Effects Side Effects During Dose Increases: Why Timing Matters Many patients notice side effects most clearly after starting therapy or after a dose increase