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Ideally, the injection is administered into a fatty layer of skin, such as: back of arm, abdomen, or flank/lumbar region

Semaglutide has 94% sequence homology with native GLP-1 [24] and three key structural differences that confer improved albumin affinity and resistance to dipeptidyl peptidase-4 degradation

Clifford BL, Sedgeman LR, Williams KJ, Morand P, Cheng A, Jarrett KE, Chan AP, Brearley-Sholto MC, Wahlstrom A, Ashby JW, Barshop W, Wohlschlegel J, Calkin AC, Liu Y, Thorell A, Meikle PJ, Drew BG, Mack JJ, Marschall HU

Free Radic Res (2004) 38:65964

Changes in urine odor are not among the most common side effects, but they can happen due to other effects of the drug