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Retatrutide may become an option in the future if: Its approved by the MHRA and recommended by NICE, which is likely several years away You havent responded well to existing GLP-1 medications, and a triple agonist offers a different approach worth trying The Phase 3 safety data on heart rate, irregular heartbeats, and dysesthesia are reassuring once its complete For most people in the UK, the choice now is between Wegovy and Mounjaro, supported by a structured weight management service

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Semaglutide side effects While semaglutide is generally tolerated pretty well, it could come with several side effects