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However, the relevance of GLP-1 signaling in genetic obesity may extend beyond this bypass mechanism

Conclusions This study analyzed public Facebook posts to examine public discussion of adverse events associated with GLP-1 RAs from 2022 to 2024

This exceeds the maximum weight loss seen with semaglutide at its highest dose (14.9% at 68 weeks)

16-18 Nausea is the most frequently reported AE among GLP-1 RAs, with rates ranging from 20% to 40% depending on the agent and dose

Discussion This study has provided evidence regarding the utilization of GLP-1 RAs, including medications such as liraglutide and semaglutide, at various dosages within real-world settings