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The study also found the drug resulted in a 19% lower risk of dying from all causes of death, something the researchers believe may indicate the potential for other, as yet unknown, benefits. Why Does Semaglutide Offer Cardiovascular Benefits

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Some individuals have genetic variants in their GLP-1 receptor gene (such as rs6923761) that affect how powerfully this hormone influences their appetite and glucose control

Moreover, some patients may interrupt their treatment once symptoms improve, not realising the long-term necessity of ongoing supplementation to prevent recurrence of deficiency symptoms